The project contains five parts 1 development and validation of software to be made publically available for modeling HITU systems, 2 development and validation of radiation force balance methods for measuring HITU acoustic output power, 3 development and validation of methods for broadband characterization of tissue mimicking materials used in HITU system characterization, 4 investigation into dependence of HITU output measurements on the type of hydrophone used, and 5 development and validation of a model for correcting needle and fiber optic hydrophones for low frequency distortion maxifort zimax sildenafil 50 mg